皮肤结节性多动脉炎。含乙肝表面抗原的免疫复合物与多形核白细胞溶酶体酶释放。
Cutaneous periarteritis nodosa. Hepatitis B surface antigen-containing immunocomplexes and polymorphonuclear-leukocyte lysosomal enzyme release.
作者信息
Van de Pette J E, Jarvis J M, Wilton J M, MacDonald D M
出版信息
Arch Dermatol. 1984 Jan;120(1):109-11. doi: 10.1001/archderm.120.1.109.
PMID:6140898
Abstract
In a patient with cold-induced cutaneous periarteritis nodosa, cryoprecipitation of a circulating hepatitis B surface antigen-containing immunocomplex resulted in phagocytosis by neutrophils and monocytes with prominent vacuolation of the cells and extracellular release of lysosomal enzymes. We believe this immunocomplex attached itself to the cell membrane and induced vacuolation and degranulation in normal neutrophils.
摘要
在一名患有冷诱导性皮肤结节性动脉周围炎的患者中，含有循环乙型肝炎表面抗原的免疫复合物的冷沉淀导致中性粒细胞和单核细胞吞噬，细胞出现明显空泡化，溶酶体酶释放到细胞外。我们认为这种免疫复合物附着于细胞膜，在正常中性粒细胞中诱导空泡化和脱颗粒。
Zotero 插件