[小鼠淋巴细胞中胸腺素组分5、前列腺素释放与Thy-1抗原出现之间的关系]
[Relation between thymosin fraction 5, prostaglandin release and Thy-1 antigen appearance in mice lymphocytes].
作者信息
Mastino A, Premrov M G, Favalli C
出版信息
Boll Soc Ital Biol Sper. 1983 Nov 30;59(11):1661-4.
PMID:6141799
Abstract
Incubation with Thymosin Fraction 5 induces a dose-dependent release of PGE2 by lymphocytes obtained from adult thymectomized mice; Indomethacin inhibits this effect. The same result was not observed in lymphocytes obtained from normal mice. PGE2 release is correlated with Thy-1 appearance on Thy-1 negative lymphocytes, after incubation with Thymosin, valutated with Bach's rosette inhibition test.
摘要
用胸腺素组分5孵育可诱导成年去胸腺小鼠淋巴细胞以剂量依赖方式释放前列腺素E2（PGE2）；吲哚美辛可抑制此效应。在正常小鼠的淋巴细胞中未观察到相同结果。在用胸腺素孵育后，通过巴赫玫瑰花结抑制试验评估，PGE2释放与Thy-1阴性淋巴细胞上Thy-1的出现相关。
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