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[中枢神经系统不同功能状态下脑结构的半球间关系]

[Interhemispheric relation of brain structures in various functional states of the central nervous system].

作者信息

Lapina I A, Iaichnikov I K, Shabanov P D, Borodkin Iu S

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1984 Jan;70(1):3-8.

PMID:6141955
Abstract

In rabbits with indwelled gold electrodes, multiminute oscillations of infraslow activity were recorded within the range from 0 to 1 Hz. The temperature of cerebral structures was recorded from symmetrical areas with the aid of thermocouple. Changes of the functional state were induced by means of 1) unilateral microstimulation of frontal neocortex with 1.5-2.5 microA; 2) administration of neurotropic activators: aethimizole and its analogue: and 3) prolonged administration of ethanole. All these influences sharply increased the natural functional interhemisphere assymmetry inducting a rearrangement of intracentral interrelationships. Use of the neurotropic activators (aethimizole and IEM-476) temporarily restored the normal interaction between the cerebral hemispheres even if the functional interhemisphere asymmetry was still obvious.

摘要

在植入金电极的兔子中,记录到了频率范围在0至1赫兹之间的数分钟超慢活动振荡。借助热电偶从对称区域记录脑结构的温度。通过以下方式诱导功能状态的变化:1)用1.5 - 2.5微安对额叶新皮层进行单侧微刺激;2)给予神经营养激活剂:乙胺咪唑及其类似物;3)长期给予乙醇。所有这些影响都急剧增加了自然的半球间功能不对称性,导致中枢内相互关系的重新排列。即使半球间功能不对称性仍然明显,使用神经营养激活剂(乙胺咪唑和IEM - 476)也能暂时恢复大脑半球之间的正常相互作用。

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