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The influence of drugs on the response of a cell culture preparation to bacterial toxins.

作者信息

Giugliano L G, Drasar B S

出版信息

J Med Microbiol. 1984 Apr;17(2):151-8. doi: 10.1099/00222615-17-2-151.

DOI:10.1099/00222615-17-2-151
PMID:6142959
Abstract

The influence was studied of lanthanum chloride, chlorpromazine hydrochloride, indomethacin and sodium cromoglycate on the morphological changes induced in Vero cells by the action of the cholera toxin, the thermolabile enterotoxin (LT) and the Vero cell cytotoxin (VT) of Escherichia coli, the enterotoxin of Clostridium perfringens, and the cytotoxin of Clostridium difficile. These drugs were able to inhibit the effects produced by C. difficile cytotoxin but not by the other toxins examined.

摘要

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