非洲爪蟾卵母细胞中由猫肌肉信使核糖核酸翻译的乙酰胆碱受体的特性
Properties of acetylcholine receptors translated by cat muscle mRNA in Xenopus oocytes.
作者信息
Miledi R, Parker I, Sumikawa K
出版信息
EMBO J. 1982;1(11):1307-12. doi: 10.1002/j.1460-2075.1982.tb01315.x.
Abstract
Poly(A)+ mRNA, extracted from denervated skeletal muscles of the cat, directs the synthesis of acetylcholine receptors in Xenopus laevis oocytes. The receptors are inserted in the oocyte membrane where they form acetylcholine receptor-channel complexes which have properties like those of the native receptors in the muscle membrane.
摘要
从猫的失神经骨骼肌中提取的多聚腺苷酸（Poly(A)）+信使核糖核酸（mRNA），可指导非洲爪蟾卵母细胞中乙酰胆碱受体的合成。这些受体插入卵母细胞膜中，在那里形成乙酰胆碱受体-通道复合物，其特性与肌膜中天然受体的特性相似。
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