In-vitro evaluation of the anticandidiasis activity of honey distillate (HY-1) compared with that of some antimycotic agents.

The susceptibility of 72 isolates of Candida albicans to the antimicrobial honey distillate fraction (HY-1) and several antimycotic agents is presented. All the isolates were sensitive to HY-1, H-115 and Jadit, while about 10% of the isolates were variably resistant to nystatin, miconazole nitrate and clotrimazole. The nystatin, miconazole nitrate and clotrimazole resistant isolates were inhibited by HY-1.