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从一对扎伊尔已婚夫妇中分离出人类嗜T淋巴细胞逆转录病毒(LAV),其中一人患有艾滋病,另一人有前驱症状。

Isolation of human T-lymphotropic retrovirus (LAV) from Zairian married couple, one with AIDS, one with prodromes.

作者信息

Ellrodt A, Barre-Sinoussi F, Le Bras P, Nugeyre M T, Palazzo L, Rey F, Brun-Vezinet F, Rouzioux C, Segond P, Caquet R

出版信息

Lancet. 1984 Jun 23;1(8391):1383-5. doi: 10.1016/s0140-6736(84)91877-4.

DOI:10.1016/s0140-6736(84)91877-4
PMID:6145837
Abstract

A Zairian married couple had been living in France since 1981. The man had acquired immunodeficiency syndrome (AIDS) and his wife had prodromes of the disorder. Infection with a human T-lymphotropic retrovirus (lymphadenopathy-associated virus) was demonstrated in both by isolation of the virus from their cultured lymphocytes and the detection of specific antibodies in serum samples. Since this virus has been isolated from patients in other AIDS risk categories, the finding of the virus in AIDS patients from the African group adds further support to the hypothesis that this human retrovirus is the AIDS aetiological agent.

摘要

一对扎伊尔夫妇自1981年起一直生活在法国。丈夫患有获得性免疫缺陷综合征(艾滋病),妻子有该疾病的前驱症状。通过从他们培养的淋巴细胞中分离出病毒以及在血清样本中检测到特异性抗体,证实两人均感染了人类嗜T淋巴细胞逆转录病毒(淋巴结病相关病毒)。由于已从其他艾滋病风险类别患者中分离出这种病毒,在非洲裔艾滋病患者中发现该病毒进一步支持了这种人类逆转录病毒是艾滋病病原体的假说。

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Isolation of human T-lymphotropic retrovirus (LAV) from Zairian married couple, one with AIDS, one with prodromes.从一对扎伊尔已婚夫妇中分离出人类嗜T淋巴细胞逆转录病毒(LAV),其中一人患有艾滋病,另一人有前驱症状。
Lancet. 1984 Jun 23;1(8391):1383-5. doi: 10.1016/s0140-6736(84)91877-4.
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Antibodies to the core protein of lymphadenopathy-associated virus (LAV) in patients with AIDS.艾滋病患者体内针对淋巴结病相关病毒(LAV)核心蛋白的抗体。
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Isolation of lymphadenopathy-associated virus (LAV) and detection of LAV antibodies from US patients with AIDS.从美国艾滋病患者中分离淋巴结病相关病毒(LAV)并检测LAV抗体。
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Seroepidemiological studies of human T-lymphotropic retrovirus type III in acquired immunodeficiency syndrome.获得性免疫缺陷综合征中人类嗜T淋巴细胞逆转录病毒III型的血清流行病学研究。
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New human T-lymphotropic retrovirus related to simian T-lymphotropic virus type III (STLV-IIIAGM).与猴嗜T淋巴细胞病毒III型(STLV-IIIAGM)相关的新型人类嗜T淋巴细胞逆转录病毒。
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Isolation of a new human retrovirus from West African patients with AIDS.从西非艾滋病患者中分离出一种新型人类逆转录病毒。
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