Lyon R
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1984;78(2):415-8. doi: 10.1016/0742-8413(84)90108-7.
Cd-binding patterns in the hepatopancreas of the crayfish (Austropotamobius pallipes) have been analysed in response to the administration of a single dose of Cd ions. Four main components, with apparent molecular weights of 3-4, 12, 20 and greater than 70 K daltons, have been isolated from soluble cell fractions. The variation in molar metal/protein ratios of these components is discussed in terms of the uptake, transfer and detoxification of Cd in the hepatopancreas. A model is proposed which describes Cd flux at the subcellular level and indicates that metallothionein-like proteins may mediate in this process.
为响应单次剂量镉离子的施用，对小龙虾（Austropotamobius pallipes）肝胰腺中的镉结合模式进行了分析。已从可溶性细胞组分中分离出四种主要成分，其表观分子量分别为3 - 4、12、20和大于70千道尔顿。根据镉在肝胰腺中的摄取、转运和解毒作用，讨论了这些成分的摩尔金属/蛋白质比率的变化。提出了一个模型，该模型描述了亚细胞水平的镉通量，并表明金属硫蛋白样蛋白可能在此过程中起介导作用。
