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妊娠大鼠乳腺中的γ-谷氨酰转移酶活性及其受卵巢激素、催乳素和胎盘催乳素的调节。

Gamma-glutamyltransferase activity in mammary gland of pregnant rats and its regulation by ovarian hormones, prolactin and placental lactogen.

作者信息

Bussmann L E, Deis R P

出版信息

Biochem J. 1984 Oct 1;223(1):275-7. doi: 10.1042/bj2230275.

Abstract

Ovariectomy and ovariectomy plus hysterectomy on day 18 of pregnancy increased gamma-glutamyltransferase activity in the mammary gland. The withdrawal of progesterone and the subsequent release of prolactin are responsible for the rise in enzyme activity. Rat placental lactogen in the absence of prolactin and progesterone is able to induce gamma-glutamyltransferase activity.

摘要

在妊娠第18天进行卵巢切除术以及卵巢切除加子宫切除术,会增加乳腺中的γ-谷氨酰转移酶活性。孕酮的撤离以及随后催乳素的释放是酶活性升高的原因。在缺乏催乳素和孕酮的情况下,大鼠胎盘催乳素能够诱导γ-谷氨酰转移酶活性。

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本文引用的文献

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Studies concerning the hormonal induction of lactogenesis by prostaglandin F2 alpha in pregnant rats.
J Steroid Biochem. 1979 Oct;11(4):1485-9. doi: 10.1016/0022-4731(79)90125-0.

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