Alföldy P, Gyódi E, Dombi E, Tóth T, Hollán S R
Haematologia (Budap). 1977;11(1-2):93-102.
Production of cellular immune reaction in subjects immunized against HLA antigens was studied by the capillary migration inhibition test in vitro and by the skin test in vivo. The majority of the immunized subjects (10 out of 13) developed a cell-mediated immunity to the donor antigens. Production of HLA antibodies was demonstrable in a smaller proportion of the cases. The complementary nature of humoral and cellular responsiveness was borne out by the present observations. The result of the skin test performed simultaneously with the migration inhibition test correlated well with the result in vitro.
通过体外毛细血管迁移抑制试验和体内皮肤试验，研究了针对HLA抗原免疫的受试者体内细胞免疫反应的产生情况。大多数免疫受试者（13例中的10例）对供体抗原产生了细胞介导的免疫。在较小比例的病例中可检测到HLA抗体的产生。本观察结果证实了体液和细胞反应性的互补性质。与迁移抑制试验同时进行的皮肤试验结果与体外试验结果相关性良好。
