DiSalvo A F, Sekhon A S, Land G A, Fleming W H
J Clin Microbiol. 1980 Mar;11(3):238-41. doi: 10.1128/jcm.11.3.238-241.1980.
Recently it was demonstrated that certain fungal pathogens could be rapidly and accurately identified on the basis of their exoantigens. Mycelial-form cultures of the Histoplasma species consistently appear to produce either H or M antigens, or both, whereas cultures of Coccidioides immitis produce tube precipitinogen, heat-labile precipitinogen, or heat-labile F antigens. Three laboratories each evaluated 48 cultures by the exoantigen procedure for the identification of Histoplasma spp. and C. immitis. One hundred forty-four cultures were tested, and 143 (99.3%) were correctly identified as Histoplama spp. or C. immitis, or neither. The simple and rapid exoantigen test appears to be a sensitive and specific method for identification of these fungi.
最近有研究表明，某些真菌病原体可以根据其外抗原被快速准确地鉴定出来。组织胞浆菌属的丝状菌培养物似乎始终会产生H抗原或M抗原，或两者皆有，而粗球孢子菌的培养物则产生试管沉淀原、热不稳定沉淀原或热不稳定F抗原。三个实验室分别通过外抗原检测程序对48份培养物进行了组织胞浆菌属和粗球孢子菌的鉴定评估。共检测了144份培养物，其中143份（99.3%）被正确鉴定为组织胞浆菌属、粗球孢子菌属，或两者皆不是。这种简单快速的外抗原检测似乎是鉴定这些真菌的一种灵敏且特异的方法。
