Motta G, Ratto G B
Minerva Med. 1980 May 12;71(19):1367-76.
A clinical research was carried out on the rheological and haemodynamic effects of various drugs commonly employed in the treatment of certain disturbances of the microcirculation. In addition to low molecular weight dextrane, a comparison was also made of three other substances theoretically capable of interfering with the fundamental relationship between viscosity, volume and haemodynamics. Assessment of the clinical signs was made both via evaluation of the peripheral haemodynamics during rest and during post-ischaemic hyperaemia and through determination of changes in blood viscosity by means of an original capillary viscosimeter. Some conclusions of a certain speculative and practical interest are drawn from the research as a whole.
针对治疗某些微循环紊乱常用的各种药物的流变学和血液动力学效应开展了一项临床研究。除低分子右旋糖酐外，还对理论上能够干扰粘度、体积与血液动力学之间基本关系的其他三种物质进行了比较。通过评估静息期和缺血后充血期的外周血液动力学以及借助一种原创的毛细管粘度计测定血液粘度变化来评估临床体征。从整个研究中得出了一些具有一定推测性和实际意义的结论。
