Emser W, Schimrigk K
Eur Neurol. 1977;16(1-6):286-91. doi: 10.1159/000114910.
A classical case of myxedema, demonstrating the typical Hoffmann syndrome (muscle weakness, hypertrophy, pseudomyotonic phenomena) and the usual rise in serum creatine phosphokinase (CPK), is discussed. Assuming that there is a CPK loss in the muscle fiber, the pseudomyotonic phenomena may be due to an increase in ADP, which in turn inhibits the calcium pump. Furthermore, light-microscopic and electron-microscopic findings are reported.
讨论了一例典型的黏液性水肿病例，该病例表现出典型的霍夫曼综合征（肌无力、肌肉肥大、假肌强直现象）以及血清肌酸磷酸激酶（CPK）的通常升高。假设肌纤维中存在CPK损失，假肌强直现象可能是由于ADP增加所致，而ADP又会抑制钙泵。此外，还报告了光镜和电镜检查结果。
