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[关于着丝粒旁异染色质的人类染色体多态性的定量评估]

[Quantitative assessment of human chromosomal polymorphism with regard to paracentromeric heterochromatin].

作者信息

Lelikova G P, Beniush V A, Tsvetkova T G

出版信息

Genetika. 1977;13(12):2195-2200.

PMID:615830
Abstract

The measurement of C-segment length in chromosomes 1, 9 and 16 of 7 individuals was carried out. The regression analysis was employed to study a change of the C-segment sizes in the process of mitotic chromosome condensation. Typical values of C-segment length for chromosomes 1, 9 and 16 are about 1.4, 1.1 and 0.8mu respectively. Among 7 individuals there was no two which had identical size of C-segments for all three chromosomes studied. In six individuals heteromorphysm of C-segments was revealed. It was found that visually detected heteromorphysm may be expressed quantitatively as ratio length of C-segments in homologous chromosomes.

摘要

对7名个体的1号、9号和16号染色体的C段长度进行了测量。采用回归分析来研究有丝分裂染色体浓缩过程中C段大小的变化。1号、9号和16号染色体C段长度的典型值分别约为1.4、1.1和0.8微米。在7名个体中,没有两人的所有三条研究染色体的C段大小完全相同。在6名个体中发现了C段的异形性。结果发现,视觉检测到的异形性可以定量地表示为同源染色体中C段的长度比。

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