Podugolnikova O A, Parfenova I V, Sushanlo H M, Prokofieva-Belgovskaja A A
Hum Genet. 1979 Jul 18;49(3):243-50. doi: 10.1007/BF00569343.
This study was made to establish a stable quantitative characteristic of C segments on chromosomes 1, 9, 16, and Y in an individual karyotype that was reproducible in successive experiments. The C segment of these chromosomes were measured in successive cultures of cells from three males and the C segments of chromosomes 1, 9, and 16 in cells from three pairs of female monozygotic twins were measured. The results show that the absolute lengths of C segments tend to vary considerably with the cell samples analyzed, while the relative length, i.e., the length of a single C segment as a percentage of the total length of all C segments of the chromosomes being studied, is more stable and can be used for individual characteristics.
本研究旨在建立个体核型中1号、9号、16号染色体及Y染色体C区段的稳定定量特征，该特征在连续实验中具有可重复性。对三名男性细胞的连续培养物中这些染色体的C区段进行了测量，并对三对女性同卵双胞胎细胞中1号、9号和16号染色体的C区段进行了测量。结果表明，C区段的绝对长度往往会因所分析的细胞样本而有很大差异，而相对长度，即单个C区段的长度占所研究染色体所有C区段总长度的百分比，则更为稳定，可用于个体特征分析。
