Shemiakin M F, Malygin A G
Mol Biol (Mosk). 1980 Nov-Dec;14(6):1392-5.
Adenosine, TMP, ADP, ATP and UpA along with guanosine and tis analogous derivatives have different reactivity towards [alpha-32P]UTP in abortive initiation reactions catalyzed by E. coli RNA polymerase on T2 DNA in the presence of Mg2+ or Mn2+. Rifampicin moderately inhibited almost all of the above mentioned reactions, except the ATP and the GTP which were even 2.5 times more reactive in the presence of this antibiotic.
腺苷、胸苷酸、二磷酸腺苷、三磷酸腺苷和UpA以及鸟苷及其类似衍生物,在镁离子或锰离子存在的情况下,由大肠杆菌RNA聚合酶在T2 DNA上催化的流产起始反应中,对[α-32P]UTP具有不同的反应活性。利福平适度抑制了几乎所有上述反应,但三磷酸腺苷和三磷酸鸟苷在这种抗生素存在时的反应活性甚至提高了2.5倍。