多核苷酸与天然膜和模型膜的相互作用。
Interaction of polynucleotides with natural and model membranes.
作者信息
Budker V G, Godovikov A A, Naumova L P, Slepneva I A
出版信息
Nucleic Acids Res. 1980 Jun 11;8(11):2499-515. doi: 10.1093/nar/8.11.2499.
Abstract
Polynucleotides adsorb on natural and model phospholipid membranes in the presence of Mg2+-cations. Adsorption of nucleic acids on membranes results in a considerable change of their secondary structure. The presence of model phosphatidylcholine membranes greatly stimulates the rate of the synthesis of RNA by E. coli RNA-polymerase on DNA template.
摘要
在Mg2+阳离子存在的情况下，多核苷酸会吸附在天然和模型磷脂膜上。核酸在膜上的吸附会导致其二级结构发生显著变化。模型磷脂酰胆碱膜的存在极大地刺激了大肠杆菌RNA聚合酶在DNA模板上合成RNA的速率。
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