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[特异性抗体对接种狂犬病疫苗者主动免疫形成的影响]

[Effect of specific antibodies on active immunity development in those inoculated with an antirabies vaccine].

作者信息

Kravchenko A T, Latypova R G, Morpgova V M, Movsesiants A A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1980 Nov(11):28-30.

PMID:6160700
Abstract

The study of the effect of gamma globulin introduced in different doses (0.5 and 0.25 ml/mg) in combination with Fermi rabies vaccine (observations on humans were made) and with cerebral rabies vaccine inactivated by UV irradiation (in animal experiments) demonstrated that the injection of the higher doses of gamma globulin resulted in lower geometrical mean of antibody titers. Therefore, in combined administration of rabies vaccine and gamma globulin for postexposure rabies prevention it is advisable to reduce the dose of gamma globulin by one-half.

摘要

对不同剂量(0.5和0.25毫升/毫克)的丙种球蛋白与费米狂犬病疫苗联合使用(对人类进行观察)以及与紫外线照射灭活的脑狂犬病疫苗联合使用(在动物实验中)的效果研究表明,注射较高剂量的丙种球蛋白会导致抗体滴度几何平均值较低。因此,在联合使用狂犬病疫苗和丙种球蛋白进行暴露后狂犬病预防时,建议将丙种球蛋白的剂量减半。

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1
[Effect of specific antibodies on active immunity development in those inoculated with an antirabies vaccine].[特异性抗体对接种狂犬病疫苗者主动免疫形成的影响]
Zh Mikrobiol Epidemiol Immunobiol. 1980 Nov(11):28-30.
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[Antigenic activity and the reactogenicity of UV ray-inactivated antirabies vaccine from the brain of sheep].[羊脑紫外线灭活抗狂犬病疫苗的抗原活性及反应原性]
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[The importance of the dispensary observation of bite victims and of those receiving antirabies treatment].
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Human antirabies gamma globulin.人抗狂犬病丙种球蛋白
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