Logie J R, Keenan R A, Whiting P H, Steyn J H
Br J Urol. 1980 Dec;52(6):526-8. doi: 10.1111/j.1464-410x.1980.tb03106.x.
A study of 39 patients having a transurethral resection (TUR) of prostate for benign prostatic hyperplasia was carried out. Large quantities of mannitol, which was used as the irrigating fluid during the procedure, were found to enter the circulation. A corresponding fall in the serum sodium levels was noted. Those patients with serum mannitol levels greater than 4000 mg/l were noted to be hypotensive and have a bradycardia. These patients were nearly all hypovolaemic and the bradycardia was felt to be inappropriate. The possibility of this being due to a combination of factors including intravascular mannitol is considered.
对39例因良性前列腺增生接受经尿道前列腺切除术（TUR）的患者进行了一项研究。术中用作冲洗液的大量甘露醇进入了循环系统。血清钠水平相应下降。血清甘露醇水平高于4000mg/l的患者出现低血压和心动过缓。这些患者几乎都存在血容量不足，且心动过缓被认为是不适当的。考虑到这可能是包括血管内甘露醇在内的多种因素共同作用的结果。
