Umeda T, Niijima T, Egawa K
Int Arch Allergy Appl Immunol. 1981;64(4):469-72. doi: 10.1159/000232728.
Phagocytosis of Staphylococcus aureus by human peripheral polymorphonuclear leucocytes in vitro in the presence of fetal calf serum was inhibited by D-galactose, N-acetyl-D-glucosamine and asialofetuin but not by fetuin. Absorption of opsonin in the serum with the bacteria, inhibition of the absorption by sugars and the effect of glycosidase treatment of the bacteria on phagocytosis showed that terminal structures of polysaccharides on the surface of bacteria play an important role in binding of opsonin to the target.
在胎牛血清存在的情况下，人外周多形核白细胞对金黄色葡萄球菌的体外吞噬作用受到D-半乳糖、N-乙酰-D-葡萄糖胺和去唾液酸胎球蛋白的抑制，但不受胎球蛋白的抑制。用细菌吸收血清中的调理素、糖对吸收的抑制作用以及糖苷酶处理细菌对吞噬作用的影响表明，细菌表面多糖的末端结构在调理素与靶标的结合中起重要作用。
