Bytzer P, Nielsen E H, Clausen J
Cell Tissue Res. 1981;216(3):647-54. doi: 10.1007/BF00238659.
Cell-surface morphology of regenerating mast cells was followed over a period of 48 h after histamine release. Control cells (not stimulated to secrete) were characterized by anastomosing folds of membrane of equal depth and width. During exocytosis these folds disappeared and were replaced by deep cup-shaped flaps of membrane evident in cells incubated for 10 min. During the first hours of regeneration these flaps fused mutually or with the plasma membrane. This activity suggests membrane retrieval, maybe specifically recycling the granule-type patches of membrane. Membrane-fusion activity was observed to some degree also after extended incubation. After 48 h of incubation the regeneration process was still not completed, as indicated by the fact that holes leading to intracellular cavities could still be found.
在组胺释放后的48小时内，对再生肥大细胞的细胞表面形态进行了跟踪观察。对照细胞（未被刺激分泌）的特征是具有深度和宽度相等的相互吻合的膜褶。在胞吐作用期间，这些褶消失，取而代之的是在孵育10分钟的细胞中可见的深杯状膜瓣。在再生的最初几个小时内，这些膜瓣相互融合或与质膜融合。这种活动表明存在膜回收，可能是特异性地回收颗粒型膜片。延长孵育后也在一定程度上观察到了膜融合活性。孵育48小时后，再生过程仍未完成，这一事实表明仍可发现通向细胞内腔的孔洞。
