Nielsen E H, Clausen J
Cell Tissue Res. 1982;224(2):465-8. doi: 10.1007/BF00216889.
Peritoneal mast cells regenerate their histamine granules in 5-6 weeks after intraperitoneal injection of the degranulating agent compound 48/80. In the beginning of the regeneration the small exocytic cavities containing the non-secreted granule remnants coalesce to a single large cavity. Later on this cavity decreases in size and becomes a small vacuole containing a very condensed material. After two weeks of regeneration mast cells are already capable of another secretory event.
腹腔注射脱颗粒剂化合物48/80后，腹膜肥大细胞在5 - 6周内重新生成其组胺颗粒。在再生开始时，含有未分泌颗粒残余物的小胞吐腔融合成一个大腔。随后，这个腔的大小减小，变成一个含有非常浓缩物质的小液泡。再生两周后，肥大细胞已经能够进行另一次分泌活动。
