Owerbach D, Nielsen J T, Rutter W J
J Biol Chem. 1981 Jun 25;256(12):6502-6.
The relative levels of pancreatic amylase mRNA closely parallel the 3-fold variation of pancreatic amylase protein levels observed in several mouse strains studied. In contrast pancreatic elastase mRNA levels were similar in these strains. Each of the strains contained the same number of amylase-like genes (about 8). The selective variation in the pancreatic amylase gene expression could be due either to differences in the numbers of active amylase genes or to different rates of synthesis and/or degradation of the amylase mRNA from a constant number of genes.
在研究的几种小鼠品系中，胰腺淀粉酶mRNA的相对水平与观察到的胰腺淀粉酶蛋白水平3倍的变化密切平行。相比之下，这些品系中胰腺弹性蛋白酶mRNA水平相似。每个品系含有的淀粉酶样基因数量相同（约8个）。胰腺淀粉酶基因表达的选择性变化可能是由于活性淀粉酶基因数量的差异，或者是由于恒定数量基因的淀粉酶mRNA合成和/或降解速率不同。
