Jakobovits A W, Gibson P R, Dudley F J
Dig Dis Sci. 1981 Aug;26(8):694-9. doi: 10.1007/BF01316857.
In a group of 50 patients seen with primary liver cell carcinoma over a period of five years, 38 had cirrhosis. In four patients the cirrhosis was due to autoimmune chronic active hepatitis. None of the patients had markers of hepatitis B virus infection, but in three of the four, serum autoantibodies were present. Coexisting autoimmune disease was present in two. Corticosteroids induced remission in all patients, and the liver disease appeared quiescent at the time primary liver cell carcinoma developed.
在一组50例原发性肝细胞癌患者中，观察期为5年，其中38例有肝硬化。4例患者的肝硬化是由自身免疫性慢性活动性肝炎引起的。所有患者均无乙肝病毒感染标志物，但4例中的3例有血清自身抗体。2例并存自身免疫性疾病。皮质类固醇使所有患者病情缓解，在原发性肝细胞癌发生时肝病似乎静止。
