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儿童期有症状的泌尿系统感染:一项为期四年的全科医疗研究中的表现以及七年时的意义和转归

Symptomatic urinary infection in childhood: presentation during a four-year study in general practice and significance and outcome at seven years.

作者信息

Brooks D, Houston I B

出版信息

J R Coll Gen Pract. 1977 Nov;27(184):678-83.

Abstract

Thirty-eight children (12 boys and 26 girls) with symptomatic urinary infection have been studied in general practice. Patients were collected over a four-year period and we report an incidence of urinary infection according to Kass's criterion of 7.7 per 1,000 girls at risk per year and 3.8 per 1,000 boys at risk per year. Eighty-four per cent of the children had symptoms which suggested an origin in the genitourinary tract. Proteus infection was found in five of the boys and only one of the girls. At the end of the four-year study period follow-up had taken place over a mean period of 25 months and recurrent infection had been demonstrated in four boys and 12 girls. All the children had an excretion urogram and two children, both girls, were found to have pyelonephritic scarring. Twelve children with recurrent infection were investigated for vesicoureteric reflux, which was found only in the two children with scarring. At seven years 31 of the children remained in the practice and, with a mean follow-up of 42 months, no significant alteration in the figures for recurrent infection was demonstrated. Guidelines are suggested for the management of childhood urinary infection in general practice.

摘要

在全科医疗中对38名有症状性泌尿道感染的儿童(12名男孩和26名女孩)进行了研究。在四年期间收集了患者,我们根据卡斯标准报告泌尿道感染的发病率为每年每1000名有风险的女孩中有7.7例,每年每1000名有风险的男孩中有3.8例。84%的儿童有提示泌尿生殖道起源的症状。在男孩中有5例发现变形杆菌感染,而女孩中仅1例。在四年研究期结束时,随访平均进行了25个月,4名男孩和12名女孩出现了反复感染。所有儿童均进行了排泄性尿路造影,发现两名女孩有肾盂肾炎瘢痕形成。对12名反复感染的儿童进行了膀胱输尿管反流检查,仅在两名有瘢痕形成的儿童中发现了反流。7岁时,31名儿童仍在该医疗机构就诊,平均随访42个月,反复感染的数据未显示出显著变化。本文提出了全科医疗中儿童泌尿道感染管理的指导原则。

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本文引用的文献

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Sex differences in childhood urinary tract infection.儿童尿路感染中的性别差异。
Arch Dis Child. 1972 Apr;47(252):227-32. doi: 10.1136/adc.47.252.227.
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Pathogenesis of the urethral syndrome in women and its diagnosis in general practice.
Lancet. 1972 Oct 28;2(7783):893-8. doi: 10.1016/s0140-6736(72)92532-9.

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