Dickinson J A
Br Med J. 1979 May 19;1(6174):1330-2. doi: 10.1136/bmj.1.6174.1330.
The incidence of symptomatic urinary tract infection in 2879 children aged under 15 years was studied over 18 months in a single general practice. Infection was diagnosed if bacterial counts in three consecutive samples exceeded 100,000/ml. The incidence of urinary tract infection was 1.7 per 1000 boys at risk per year and 3.1 per 1000 girls. These values are lower than those of comparable studies, possibly because of the stricter diagnostic criterion used in the study. Urinary pus cell counts were also carried out and sometimes found to be misleading. Of the 14 children found to have an infection, three had a radiological abnormality. Five of the children had a recurrence of infection within the first two years, and one an asymptomatic bacteriuria seven years after diagnosis. Only six out of 34 children presenting with dysuria had infected urine, and an association was discovered between abacterial dysuria (or the urethral syndrome) in the remainder and a concurrent upper respiratory tract infection. All children should undergo radiological investigation after their first confirmed infection. Diagnosis and management could be improved by providing all general practitioners with a semiquantitative method of urine culture such as the dip slide.
在一家普通诊所对2879名15岁以下儿童进行了为期18个月的有症状尿路感染发病率研究。如果连续三个样本中的细菌计数超过100,000/ml,则诊断为感染。尿路感染的发病率为每年每1000名有风险的男孩中有1.7例,每1000名女孩中有3.1例。这些值低于类似研究中的值,可能是因为该研究中使用了更严格的诊断标准。还进行了尿脓细胞计数,有时发现其具有误导性。在发现感染的14名儿童中,有3名有放射学异常。5名儿童在头两年内感染复发,1名在诊断后7年有无症状菌尿。在34名出现排尿困难的儿童中,只有6名尿液感染,并且在其余儿童的无菌性排尿困难(或尿道综合征)与并发的上呼吸道感染之间发现了关联。所有儿童在首次确诊感染后都应接受放射学检查。通过为所有全科医生提供一种半定量尿培养方法(如浸片法),可以改善诊断和管理。