McKerrow W, Davidson-Lamb N, Jones P F
Br Med J (Clin Res Ed). 1984 Aug 4;289(6440):299-303. doi: 10.1136/bmj.289.6440.299.
During 1968-77, 572 consecutive children with one or more positive urine cultures who were referred by their family doctors to one paediatric surgical outpatient clinic were investigated and prospectively recorded. An abnormality requiring treatment was found in 45%. The yield of positive findings and need for operation were greater in those referred after one infection than in those with recurrent infection. Among those under 2 years old 90% had an abnormality. One third of children with vesicoureteric reflux showed renal scarring at the time of first attendance. The results of medical and surgical treatment over five to 15 years of follow up were analysed. They emphasised the importance of culturing the urine whenever there may be urinary infection in a child and of investigating immediately those with a positive urine culture.
在1968年至1977年期间，对572名由家庭医生转介至一家儿科外科门诊的连续患儿进行了调查，并进行了前瞻性记录，这些患儿的尿液培养结果有一项或多项呈阳性。发现45%的患儿存在需要治疗的异常情况。单次感染后转诊的患儿中阳性发现率和手术需求高于反复感染的患儿。在2岁以下的患儿中，90%存在异常情况。三分之一的膀胱输尿管反流患儿在首次就诊时就出现了肾瘢痕形成。对5至15年随访期间的药物和手术治疗结果进行了分析。结果强调了在儿童可能存在尿路感染时进行尿液培养的重要性，以及对尿液培养呈阳性的患儿立即进行检查的重要性。
