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引用本文的文献

1
Interferons and other cytokines in head and neck cancer.头颈部癌症中的干扰素及其他细胞因子。
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2
Biological therapy of cancer.
Breast Cancer Res Treat. 1986;7(1):5-14. doi: 10.1007/BF01886730.

本文引用的文献

1
Prognostic significance of histologic host response in cancer of the larynx or hypopharynx.喉或下咽癌组织学宿主反应的预后意义
Cancer. 1971 Nov;28(5):1255-65. doi: 10.1002/1097-0142(1971)28:5<1255::aid-cncr2820280524>3.0.co;2-a.
2
Immunologic assessment of regional lymph node histology in relation to survival in head and neck carcinoma.头颈部癌区域淋巴结组织学与生存相关的免疫评估。
Cancer. 1976 Feb;37(2):697-705. doi: 10.1002/1097-0142(197602)37:2<697::aid-cncr2820370214>3.0.co;2-i.
3
[Morphologic findings in the immunobiology of laryngeal cancer].[喉癌免疫生物学中的形态学发现]
Acta Otolaryngol. 1975 Mar-Apr;79(3-4):166-71.
4
Preliminary observations on the effect of human leukocyte interferon in non-Hodgkin's lymphoma.人白细胞干扰素对非霍奇金淋巴瘤疗效的初步观察
N Engl J Med. 1978 Dec 28;299(26):1449-53. doi: 10.1056/NEJM197812282992608.
5
Interferons: anti-neoplastic drugs?干扰素：抗肿瘤药物？
Blut. 1977 Sep 18;35(4):277-88. doi: 10.1007/BF00996140.
6
Mechanisms of tumor immunity. An overview.肿瘤免疫机制。概述。
Am J Pathol. 1978 Nov;93(2):449-58.
7
Interferon and spontaneous cytotoxicity in man. II. Studies in patients receiving exogenous leukocyte interferon.人体中的干扰素与自发细胞毒性。II. 接受外源性白细胞干扰素治疗患者的研究。
Acta Med Scand. 1978;204(6):477-83.
8
Histological classification of larynx and hypopharynx cancers and their clinical implications. Pathologic aspects of 2052 malignant neoplasms diagnosed at the ORL Department of Padua University from 1966 to 1976.喉癌和下咽癌的组织学分类及其临床意义。1966年至1976年在帕多瓦大学耳鼻喉科诊断的2052例恶性肿瘤的病理学情况。
Acta Otolaryngol Suppl. 1976;342:1-88.

干扰素在皮肤及头颈部肿瘤治疗中的作用。

Effect of interferon in therapy of skin and head and neck tumors.

作者信息

Padovan I, Brodarec I, Ikić D, Knezević M, Soos E

出版信息

J Cancer Res Clin Oncol. 1981;100(3):295-310. doi: 10.1007/BF00410690.

DOI:10.1007/BF00410690
PMID:6168641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12253505/
Abstract

The clinical experimental model of HLI application in the therapy of skin and mucosal cancers of the head and neck has opened new prospects in HLI utilization. Based on clinical observations and research it may be concluded that HLI, if applied topically in the area of the tumor, may induce its disappearance or regression. If applied presurgically, it blocks the dispersion of neocytes during surgery. Also, HLI inhibits metastatic dissemination of malignant tumors and therefore might reduce the percentage of patients with recurrence, decreasing the chance of survival of any other primary tumor.

摘要

高剂量光免疫疗法（HLI）应用于头颈部皮肤和黏膜癌治疗的临床实验模型为HLI的利用开辟了新前景。基于临床观察和研究可以得出结论，HLI如果局部应用于肿瘤区域，可能会使其消失或缩小。如果在手术前应用，它会在手术过程中阻止新生细胞的扩散。此外，HLI可抑制恶性肿瘤的转移扩散，因此可能会降低复发患者的比例，减少其他原发肿瘤的生存几率。