Euler M, Kiessling J
Electroencephalogr Clin Neurophysiol. 1981 Nov;52(5):400-4. doi: 10.1016/0013-4694(81)90022-5.
Frequency-following responses (FFR) from continuous tone stimulation were investigated by lock-in analysis. The technique is superior to conventional tone-burst stimulation, because it allows continuous registration of the response parameters with sweeping frequency. The scalp recorded FFR consists of at least two components separable from each other by their phase/frequency relationship. The microphonic component that dominates in ipsilateral records shows latencies of about 0.5 msec with negligible dispersion and must therefore originate in the basal cochlear turn. The neural component exhibits considerable dispersion, reflecting the travelling wave delay up to the region of best frequency. These long cochlear time delays are consistent with an apical FFR origin, and brain stem sources of the continuous tone response appear to be questionable. The present FFR analysis technique opens up a very direct and comprehensive way to assess the integrity of the entire inner ear for high frequency basal and low frequency apical cochlear regions as well.
通过锁相分析研究了连续纯音刺激产生的频率跟随反应(FFR)。该技术优于传统的短纯音刺激,因为它允许在频率扫描时连续记录反应参数。头皮记录的FFR至少由两个成分组成,可通过它们的相位/频率关系相互分离。在同侧记录中占主导的微音器成分显示出约0.5毫秒的潜伏期,离散度可忽略不计,因此必定起源于耳蜗基部转弯处。神经成分表现出相当大的离散度,反映了行波延迟直至最佳频率区域。这些较长的耳蜗时间延迟与FFR起源于顶部相一致,连续纯音反应的脑干来源似乎存在疑问。目前的FFR分析技术为评估整个内耳高频基部和低频顶部耳蜗区域的完整性开辟了一种非常直接和全面的方法。