Reynolds J C, Inman R D, Kimberly R P, Chuong J H, Kovacs J E, Walsh M B
Medicine (Baltimore). 1982 Jan;61(1):25-32. doi: 10.1097/00005792-198201000-00003.
A retrospective study was undertaken of patients with systemic lupus erythematosus in whom serum amylase had been determined. Sixty-three patients were identified, and of these 53 had abdominal pain at the time of the amylase measurement. Twenty-seven (51 percent) had a normal serum amylase, and 12 of this group had defined reasons for the abdominal pain. Of the 26 patients with hyperamylasemia, 6 had extrapancreatic causes for the elevated amylase. In 20 patients (37 percent of those with abdominal pain) the clinical diagnosis of pancreatitis was made. The amylase levels showed no correlation with renal function nor with dose of corticosteroid. Four patients with pancreatitis were identified in whom no contributing factor other than SLE could be ascertained. No serious complication of the pancreatitis was seen, and recovery occurred despite continued steroid therapy. Pancreatitis is not a rare occurrence in SLE, and may be related in part to the vasculitis seen during periods of disease activity.
对测定过血清淀粉酶的系统性红斑狼疮患者进行了一项回顾性研究。共确定了63例患者，其中53例在测定淀粉酶时伴有腹痛。27例（51%）血清淀粉酶正常，该组中有12例有明确的腹痛原因。在26例高淀粉酶血症患者中，6例淀粉酶升高有胰腺外原因。20例患者（占腹痛患者的37%）被临床诊断为胰腺炎。淀粉酶水平与肾功能及皮质类固醇剂量均无相关性。确定有4例胰腺炎患者，除系统性红斑狼疮外未发现其他促成因素。未观察到胰腺炎的严重并发症，尽管继续进行类固醇治疗，患者仍康复了。胰腺炎在系统性红斑狼疮中并非罕见，可能部分与疾病活动期出现的血管炎有关。
