Sørensen J P, Jensen M K, Jersild C
Mutat Res. 1981 Oct;90(2):143-7. doi: 10.1016/0165-1218(81)90077-x.
Mitogen-stimulated lymphocytes from 8 healthy donors were exposed to interferon, and cytogenetic studies were preformed. The response of lymphocytes to the mitogens phytohemagglutinin (PHA), concanavalin A (con A) and pokeweed mitogen (PWM) was inhibited by interferon, whereas an increased number of structural chromosomal aberrations was not detected. Further investigations of the cytogenetic effects of interferon are needed.
来自8名健康供体的丝裂原刺激淋巴细胞暴露于干扰素，并进行了细胞遗传学研究。干扰素抑制了淋巴细胞对植物血凝素（PHA）、刀豆球蛋白A（Con A）和商陆有丝分裂原（PWM）的丝裂原反应，而未检测到结构染色体畸变数量增加。需要对干扰素的细胞遗传学效应进行进一步研究。
