Chaouat D, Benlahrache C, Yannoutsos H, Hoffman H, Fruchart M C, Le Parc J M, Paolaggi J B, Auquier L
Nouv Presse Med. 1982 Jan 16;11(2):101-4.
The authors studied 31 patients with either rhizomelic pseudopolyarthritis or Horton's disease. Contrary to others, they found no significant correlation between these diseases and hepatitis B virus infection or HLA gene. However, beta 2 microglobulin assays showed that it was significantly higher in these patients than in a control population. In the absence of close correlation between beta 2 microglobulin levels and those of inflammatory proteins, it is suggested that the rise in microglobulin reflected an immunological mechanism requiring further investigation.
作者对31例患有肢根性假多关节炎或霍顿病的患者进行了研究。与其他人的研究结果相反，他们发现这些疾病与乙型肝炎病毒感染或HLA基因之间没有显著相关性。然而，β2微球蛋白检测显示，这些患者体内的β2微球蛋白水平显著高于对照组人群。由于β2微球蛋白水平与炎症蛋白水平之间缺乏密切相关性，因此有人提出，微球蛋白水平的升高反映了一种需要进一步研究的免疫机制。
