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[人类Y染色体异染色质区域的结构多态性]

[Structural polymorphism of the heterochromatin region of human Y chromosome].

作者信息

Kovaleva N V

出版信息

Tsitologiia. 1981 Dec;23(12):1423-7.

PMID:6173947
Abstract

A comparison of sequential stained Y-chromosomes from 13 individuals has shown that Q- and C-blocks are not identical. Several polymorphic variants of positively stained regions were revealed. These data suggest the existence of no less than 4 types of structures in the heterochromatic region of Y-chromosome, that vary independently and reflect the localization of different satellite DNA sequences: 1) this region is positively stained using both Q- and C-methods; 2) the proximal Q-negative block, positively stained by C-method; 3) the distal Q-negative block, positively stained by C-method; 4) the distal Q-positive block not revealed by C-method. For the complete revealing of heterochromatic constitution of human Y-chromosome both Q- and C-methods are needed.

摘要

对13个个体的连续染色Y染色体进行比较后发现,Q块和C块并不相同。发现了几个阳性染色区域的多态变体。这些数据表明,Y染色体异染色质区域至少存在4种结构类型,它们独立变化并反映了不同卫星DNA序列的定位:1)该区域用Q法和C法染色均呈阳性;2)近端Q阴性块,C法染色呈阳性;3)远端Q阴性块,C法染色呈阳性;4)远端Q阳性块,C法未显示。为了完整揭示人类Y染色体的异染色质组成,需要Q法和C法。

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