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兔抗梯牧草抗原B辅助因子及抗小鼠梯牧草IgE抗血清抗独特型特性的制备与鉴定

Preparation and characterization of the anti-idiotypic properties of rabbit anti-timothy antigen B helper factor and anti-mouse timothy IgE antisera.

作者信息

Malley A, Brandt C J, Deppe L B

出版信息

Immunology. 1982 Feb;45(2):217-25.

PMID:6174420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1555265/
Abstract

with AgB-primed B or T cells and injected into syngeneic X-irradiated recipients. Anti-THF and anti-Eid purified by an AgB-specific T suppressor factor (TSF) affi-gel adsorbent retain their ability to specifically initiate [3H]-thymidine incorporation of AgB-primed T cells. The data indicate that both anti-THF and anti-Eid recognize unique determinants present on AgB-specific T-helper, T-suppressor and B cells, and suggest that the receptors on AgB-specific T and B cells share cross-reactive idiotypic determinants.

摘要

用经AgB致敏的B或T细胞，并注射到同基因X射线照射的受体中。通过AgB特异性T抑制因子（TSF）琼脂糖凝胶吸附剂纯化的抗THF和抗Eid保留了特异性启动经AgB致敏的T细胞掺入[3H] - 胸腺嘧啶核苷的能力。数据表明，抗THF和抗Eid都识别存在于AgB特异性T辅助细胞、T抑制细胞和B细胞上的独特决定簇，并表明AgB特异性T细胞和B细胞上的受体共享交叉反应性独特型决定簇。

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引用本文的文献

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Preparation and characterization of a monoclonal anti-T helper factor antibody.一种抗T辅助因子单克隆抗体的制备与鉴定
Immunology. 1984 Apr;51(4):765-72.
2
Regulation of timothy grass pollen IgE antibody formation. I. In-vitro induction of suppressor T cells by soluble T suppressor factors.梯牧草花粉IgE抗体形成的调节。I. 可溶性T抑制因子对抑制性T细胞的体外诱导
Immunology. 1983 Jul;49(3):463-9.
3
Anti-idiotype regulation of the formation of IgE antibody to timothy grass pollen. II. In vitro induction of suppressor T cells in mini-Marbrook cultures.抗 Timothy 草花粉 IgE 抗体形成的独特型调节。II. 小型 Marbrook 培养物中抑制性 T 细胞的体外诱导。
Immunology. 1983 Jan;48(1):93-9.
4
Anti-idiotype regulation of timothy grass pollen IgE antibody formation. I. In vivo induction of suppressor T cells.梯牧草花粉IgE抗体形成的抗独特型调节。I. 体内抑制性T细胞的诱导。
Immunology. 1982 Jul;46(3):653-9.

本文引用的文献

1
Induction of T and B cell immunity by anti-idiotypic antibody.抗独特型抗体诱导T细胞和B细胞免疫
Eur J Immunol. 1975 Oct;5(10):661-6. doi: 10.1002/eji.1830051002.
2
T-cell-priming characteristics of modified timothy grass pollen antigen B1.改良型梯牧草花粉抗原B1的T细胞启动特性
Int Arch Allergy Appl Immunol. 1980;62(3):276-84. doi: 10.1159/000232523.
3
Biologic properties of a non-precipitating antigen from timothy pollen extracts.梯牧草花粉提取物中一种非沉淀性抗原的生物学特性
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4
A simplified method for cyanogen bromide activation of agarose for affinity chromatography.一种用于亲和色谱的琼脂糖溴化氰活化的简化方法。
Anal Biochem. 1974 Jul;60(1):149-52. doi: 10.1016/0003-2697(74)90139-0.
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A rapid method for the isolation of functional thymus-derived murine lymphocytes.一种分离功能性胸腺来源的小鼠淋巴细胞的快速方法。
Eur J Immunol. 1973 Oct;3(10):645-9. doi: 10.1002/eji.1830031011.
6
Response of mouse splenic lymphocytes to timothy pollen antigens in a microculture system.小鼠脾淋巴细胞在微量培养系统中对梯牧草花粉抗原的反应。
J Immunol. 1975 Dec;115(6):1533-7.
7
Mouse B and T lymphocyte responses to purified timothy pollen antigens in vitro.小鼠B淋巴细胞和T淋巴细胞对体外纯化的梯牧草花粉抗原的反应。
J Immunol. 1976 Dec;117(6):2137-42.
8
"Panning" for lymphocytes: a method for cell selection.“淘选”淋巴细胞：一种细胞选择方法。
Proc Natl Acad Sci U S A. 1978 Jun;75(6):2844-8. doi: 10.1073/pnas.75.6.2844.
9
Anti-idiotype induced regulation of helper cell function for the response to phosphorylcholine in adult BALB/c mice.抗独特型诱导成年BALB/c小鼠对磷酸胆碱反应中辅助性细胞功能的调节。
J Exp Med. 1978 Nov 1;148(5):1216-27. doi: 10.1084/jem.148.5.1216.
10
Preparation of high titered rabbit anti-mouse IgE sera.高滴度兔抗小鼠IgE血清的制备。
Immunol Commun. 1977;6(5):473-82. doi: 10.3109/08820137709094146.

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