Epstein L B, Gupta S
J Clin Immunol. 1981 Jul;1(3):186-94. doi: 10.1007/BF00922762.
Human T micron, T gamma, and T PHI lymphocyte subpopulations have the capacity to respond to phytohemagglutinin (PHA) in vitro with proliferation and the production of a pH 2 and heat-labile gamma interferon. This occurs both when the subsets are isolated by direct rosetting techniques or by negative selection. Macrophages enhance the production of the gamma interferon by each lymphocyte subset and do not themselves produce gamma interferon in response to products of PHA-activated lymphocyte subsets. Thus our studies indicate that subpopulations of T lymphocytes known to differ with regard to morphology, surface receptors, RNA content, response to corticosteroids and X-irradiation, and other functional capabilities do not differ with regard to their capacity to produce gamma interferon.
人类Tμ、Tγ和Tɸ淋巴细胞亚群有能力在体外对植物血凝素（PHA）作出反应，表现为增殖并产生pH2且不耐热的γ干扰素。当通过直接玫瑰花结技术或阴性选择分离这些亚群时，都会出现这种情况。巨噬细胞可增强每个淋巴细胞亚群的γ干扰素产生，而其自身不会因PHA激活的淋巴细胞亚群产物而产生γ干扰素。因此，我们的研究表明，已知在形态、表面受体、RNA含量、对皮质类固醇和X射线照射的反应以及其他功能能力方面存在差异的T淋巴细胞亚群，在产生γ干扰素的能力方面并无差异。
