• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Antigen-specific production of immune interferon by T Cells lines.T细胞系对抗原特异性产生免疫干扰素。
J Exp Med. 1982 Apr 1;155(4):1204-9. doi: 10.1084/jem.155.4.1204.
2
Antigen-specificity of continuous T cell lines.连续T细胞系的抗原特异性
Curr Top Microbiol Immunol. 1982;100:249-55. doi: 10.1007/978-3-642-68586-6_28.
3
Cytotoxic T lymphocytes produce immune interferon in response to antigen or mitogen.细胞毒性T淋巴细胞在对抗抗原或有丝分裂原时会产生免疫干扰素。
J Exp Med. 1982 Apr 1;155(4):1198-203. doi: 10.1084/jem.155.4.1198.
4
Hapten-specific T cell lines mediating delayed hypersensitivity to contact-sensitizing agents.对半抗原致敏剂介导迟发型超敏反应的半抗原特异性T细胞系。
J Exp Med. 1982 Jul 1;156(1):300-5. doi: 10.1084/jem.156.1.300.
5
Regulation of the production of immune interferon and cytotoxic T lymphocytes by interleukin 2.白细胞介素2对免疫干扰素和细胞毒性T淋巴细胞产生的调节作用。
J Immunol. 1981 Mar;126(3):1120-5.
6
Production of interferon in the murine mixed lymphocyte culture. II. Interferon production is a T cell-dependent function, independent of proliferation.小鼠混合淋巴细胞培养中干扰素的产生。II. 干扰素的产生是一种T细胞依赖性功能，与增殖无关。
Eur J Immunol. 1979 Oct;9(10):824-6. doi: 10.1002/eji.1830091015.
7
Identification of a subpopulation of mouse lymphoid cells required for interferon production after stimulation with mitogens.
J Immunol. 1974 Apr;112(4):1589-93.
8
The quantitative production of interferon by mitogen-stimulated mouse lymphocytes as a function of age and its effect on the lymphocytes proliferative response.丝裂原刺激的小鼠淋巴细胞产生干扰素的定量情况与年龄的关系及其对淋巴细胞增殖反应的影响。
J Immunol. 1977 Apr;118(4):1366-9.
9
In vitro evidence from anti-hapten antibody responses for T helper and suppressor cells directed against major histocompatibility antigens in the mouse. Participation of I region determinants in the induction of T helper cells.小鼠中针对主要组织相容性抗原的T辅助细胞和抑制细胞的抗半抗原抗体反应的体外证据。I区决定簇在T辅助细胞诱导中的参与。
Eur J Immunol. 1979 Jul;9(7):561-9. doi: 10.1002/eji.1830090712.
10
Major histocompatibility complex-restricted and unrestricted T helper cells recognizing minor histocompatibility antigens of B cell surfaces.识别B细胞表面次要组织相容性抗原的主要组织相容性复合体限制和非限制的辅助性T细胞。
Eur J Immunol. 1980 Jul;10(7):535-41. doi: 10.1002/eji.1830100710.

引用本文的文献

1
Human immunodeficiency virus type 1-specific cytotoxic T lymphocytes release gamma interferon, tumor necrosis factor alpha (TNF-alpha), and TNF-beta when they encounter their target antigens.1型人类免疫缺陷病毒特异性细胞毒性T淋巴细胞在遇到其靶抗原时会释放γ干扰素、肿瘤坏死因子α（TNF-α）和肿瘤坏死因子β。
J Virol. 1993 May;67(5):2844-52. doi: 10.1128/JVI.67.5.2844-2852.1993.
2
Anti-T-cell idiotype activity in serum of mice injected with syngeneic hapten-specific T-cell lines.注射同基因半抗原特异性T细胞系的小鼠血清中的抗T细胞独特型活性。
Proc Natl Acad Sci U S A. 1982 Nov;79(21):6671-4. doi: 10.1073/pnas.79.21.6671.
3
Specific adoptive immunotherapy of malignant glioma with long-term cytotoxic T lymphocyte line expanded in T-cell growth factor. Experimental study and future prospects.用在T细胞生长因子中扩增的长期细胞毒性T淋巴细胞系对恶性胶质瘤进行特异性过继免疫治疗。实验研究及未来展望。
Neurosurg Rev. 1984;7(1):37-54. doi: 10.1007/BF01743289.
4
Monoclonal antibodies against murine gamma interferon.抗小鼠γ干扰素单克隆抗体
Proc Natl Acad Sci U S A. 1984 Jul;81(14):4515-9. doi: 10.1073/pnas.81.14.4515.
5
Immune human lymphocytes produce an acid-labile alpha-interferon.免疫的人体淋巴细胞产生一种对酸不稳定的α干扰素。
J Exp Med. 1983 Mar 1;157(3):1059-63. doi: 10.1084/jem.157.3.1059.
6
Delayed hypersensitivity induced by anti-T-cell-line antisera is enhanced by pertussigen and not restricted by histocompatibility genes.抗T细胞系抗血清诱导的迟发型超敏反应可被百日咳菌素增强，且不受组织相容性基因限制。
Proc Natl Acad Sci U S A. 1983 Apr;80(7):2036-9. doi: 10.1073/pnas.80.7.2036.
7
Interferon-gamma-like molecule induces Ia antigens on cultured mast cell progenitors.干扰素-γ样分子可诱导培养的肥大细胞祖细胞上的Ia抗原。
Proc Natl Acad Sci U S A. 1982 Nov;79(22):6989-93. doi: 10.1073/pnas.79.22.6989.

本文引用的文献

1
Specificity, Ly phenotype, and H-2 compatibility requirements of effector cells in delayed-type hypersensitivity responses to murine influenza virus infection.对鼠流感病毒感染的迟发型超敏反应中效应细胞的特异性、淋巴细胞表型及H-2相容性要求
J Exp Med. 1980 Apr 1;151(4):815-26. doi: 10.1084/jem.151.4.815.
2
Adoptive transfer of delayed-type hypersensitivity to Sendai virus. III. Effect of H-2 mutations on recognition by K, D-region restricted T effector lymphocytes.对仙台病毒迟发型超敏反应的过继转移。III. H-2突变对K、D区限制性T效应淋巴细胞识别的影响。
Immunogenetics. 1981 Mar 1;12(5-6):579-86. doi: 10.1007/BF01561698.
3
Immune (gamma) interferon produced by a human T-lymphoblast cell line.由人T淋巴细胞母细胞系产生的免疫（γ）干扰素。
Nature. 1981 Aug 27;292(5826):842-4. doi: 10.1038/292842a0.
4
Human gamma interferon production by leukocytes induced with monoclonal antibodies recognizing T cells.用识别T细胞的单克隆抗体诱导白细胞产生人γ干扰素。
J Immunol. 1981 Sep;127(3):1197-200.
5
Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity.迟发型超敏反应小鼠循环中迁移抑制因子和干扰素的产生及特性
J Immunol. 1973 Dec;111(6):1914-22.
6
Immune interferon production by lymphoid cells: role in the inhibition of herpesviruses.淋巴细胞产生免疫干扰素：在抑制疱疹病毒中的作用。
Infect Immun. 1976 Jun;13(6):1567-78. doi: 10.1128/iai.13.6.1567-1578.1976.
7
H-2 gene complex restricts transfer of delayed-type hypersensitivity in mice.H-2基因复合体限制小鼠迟发型超敏反应的转移。
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5095-8. doi: 10.1073/pnas.72.12.5095.
8
Inability of measles virus temperature-sensitive mutants to induce interferon.麻疹病毒温度敏感突变体诱导干扰素的无能性。
Virology. 1977 Jan;76(1):409-15. doi: 10.1016/0042-6822(77)90312-9.
9
In vitro production and cellular origin of murine type II interferon.小鼠II型干扰素的体外产生及细胞起源
Immunology. 1979 Apr;36(4):883-90.
10
Production of an antiviral factor by murine spleen cells after treatment with Corynebacterium parvum.用短小棒状杆菌处理后小鼠脾细胞产生抗病毒因子。
Cell Immunol. 1977 Jun 1;31(1):172-6. doi: 10.1016/0008-8749(77)90016-8.

T细胞系对抗原特异性产生免疫干扰素。

Antigen-specific production of immune interferon by T Cells lines.

作者信息

McKimm-Breschkin J L, Mottram P L, Thomas W R, Miller J F

出版信息

J Exp Med. 1982 Apr 1;155(4):1204-9. doi: 10.1084/jem.155.4.1204.

DOI:10.1084/jem.155.4.1204
PMID:6174674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2186660/
Abstract

Continuous cultures of T cells reactive to the hapten 4-ethoxymethylene-2-phenyloxazolone were tested for interferon production after antigenic stimulation in vitro. Induction of interferon was antigen-specific and also restricted by the I region of the major histocompatibility complex. Kinetics of antigen induced interferon production were different from those reported for mitogen induced synthesis.

摘要

对半抗原4-乙氧基亚甲基-2-苯基恶唑酮有反应的T细胞连续培养物，在体外经抗原刺激后检测其干扰素生成情况。干扰素的诱导具有抗原特异性，并且也受主要组织相容性复合体I区的限制。抗原诱导的干扰素生成动力学与有丝分裂原诱导合成所报道的动力学不同。