免疫的人体淋巴细胞产生一种对酸不稳定的α干扰素。
Immune human lymphocytes produce an acid-labile alpha-interferon.
作者信息
Balkwill F R, Griffin D B, Band H A, Beverley P C
出版信息
J Exp Med. 1983 Mar 1;157(3):1059-63. doi: 10.1084/jem.157.3.1059.
Abstract
We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of alpha-IFN and physicochemical properties of gamma-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune disease (10). The system described here will be useful in elucidating the biological significance and cell of origin of this IFN.
摘要
我们在本文中描述了一种新型人类干扰素（IFN），它具有α-干扰素的抗原性和跨物种反应性以及γ-干扰素的物理化学特性。这种干扰素是在免疫反应期间由正常外周血单核细胞产生的，但也与自身免疫性疾病有关（10）。这里描述的系统将有助于阐明这种干扰素的生物学意义和起源细胞。
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本文引用的文献
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Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin.植物血球凝集素诱导人白细胞产生干扰素样病毒抑制剂。
Science. 1965 Jul 16;149(3681):310-1. doi: 10.1126/science.149.3681.310.
2
Analysis and purification of human lymphoblastoid (Namalwa) interferon using a monoclonal antibody.使用单克隆抗体对人淋巴母细胞样（Namalwa）干扰素进行分析与纯化。
J Gen Virol. 1982 Nov;63 (Pt 1):207-12. doi: 10.1099/0022-1317-63-1-207.
3
Long-term human T-helper lines producing specific helper factor reactive to influenza virus.产生对流感病毒有反应的特异性辅助因子的长期人类T辅助细胞系。
Nature. 1981 Nov 12;294(5837):166-8. doi: 10.1038/294166a0.
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J Interferon Res. 1981 Feb;1(2):233-44. doi: 10.1089/jir.1981.1.233.
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Production of immune interferon by human cytotoxic T cell clones.人细胞毒性T细胞克隆产生免疫干扰素。
J Immunol. 1982 Aug;129(2):450-1.
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Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon.系统性红斑狼疮：人血清中存在一种异常的酸不稳定白细胞干扰素。
Science. 1982 Apr 23;216(4544):429-31. doi: 10.1126/science.6176024.
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