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1
Effect of highly selective vagotomy on pancreatic exocrine function and on cholecystokinin and gastrin release.高选择性迷走神经切断术对胰腺外分泌功能及胆囊收缩素和胃泌素释放的影响。
Gut. 1982 Jul;23(7):553-7. doi: 10.1136/gut.23.7.553.
2
Effect of endogenous pancreatic glucagon on gastric acid secretion in patients with duodenal ulcer before and after parietal cell vagotomy.内源性胰高血糖素对十二指肠溃疡患者壁细胞迷走神经切断术前、后胃酸分泌的影响。
Gut. 1981 May;22(5):359-62. doi: 10.1136/gut.22.5.359.
3
[The role of gastrin in duodenal ulceration (author's transl)].胃泌素在十二指肠溃疡形成中的作用（作者译）
Zentralbl Chir. 1982;107(4):193-9.
4
[Serum gastrin and gastric acid level following vagotomy without pyloroplasty and partial gastrectomy (BI) (author's transl)].无幽门成形术的迷走神经切断术和胃部分切除术（毕罗Ⅰ式）后血清胃泌素和胃酸水平（作者译）
Zentralbl Chir. 1982;107(4):200-6.
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Pancreatic exocrine secretion. Release of gastrin and cholecystokinin in response to bombesin in pigs.胰腺外分泌。猪体内胃泌素和胆囊收缩素对蛙皮素的反应释放。
Arch Surg. 1984 Jul;119(7):825-8. doi: 10.1001/archsurg.1984.01390190063014.
6
24-hour intragastric acidity and plasma gastrin after omeprazole treatment and after proximal gastric vagotomy in duodenal ulcer patients.十二指肠溃疡患者接受奥美拉唑治疗及近端胃迷走神经切断术后的24小时胃内酸度和血浆胃泌素水平
Gastroenterology. 1990 Dec;99(6):1593-8. doi: 10.1016/0016-5085(90)90462-a.
7
[Effect of vagotomy on gastrin secretion in patients with duodenal ulcer].
Ter Arkh. 1985;57(2):11-5.
8
Selective proximal vagotomy in the treatment of duodenal ulcer.
World J Surg. 1980 May;4(3):347-52. doi: 10.1007/BF02393401.
9
Proximal gastric vagotomy interferes with a fundic inhibitory mechanism. A hypothesis for the high recurrence rate of peptic ulceration.近端胃迷走神经切断术干扰了胃底抑制机制。这是消化性溃疡高复发率的一种假说。
Am J Surg. 1983 Jul;146(1):51-6. doi: 10.1016/0002-9610(83)90258-1.
10
[Exocrine function of the pancreas after vagotomy with economical gastric resection].[经济性胃切除术后迷走神经切断术对胰腺外分泌功能的影响]
Vestn Khir Im I I Grek. 1975 Aug;115(8):8-12.

引用本文的文献

1
Gallbladder motility, gallstones, and the surgeon.胆囊运动功能、胆结石与外科医生
Dig Dis Sci. 1995 Nov;40(11):2323-35. doi: 10.1007/BF02063233.
2
Relationship between gastric emptying of a solid meal and emptying of the gall bladder before and after vagotomy.迷走神经切断术前和术后固体餐胃排空与胆囊排空之间的关系。
Gut. 1987 Jul;28(7):855-63. doi: 10.1136/gut.28.7.855.
3
Laboratory tests in the diagnosis of the chronic pancreatic diseases. Part 2. Tests of pancreatic secretion.慢性胰腺疾病诊断中的实验室检查。第2部分。胰腺分泌功能检查。
Int J Pancreatol. 1987 Aug;2(4):211-21. doi: 10.1007/BF02788399.

本文引用的文献

1
Simple method for estimating trypsin.估算胰蛋白酶的简易方法。
Gut. 1967 Aug;8(4):415-6. doi: 10.1136/gut.8.4.415.
2
STEATORRHOEA AND DIARRHOEA AFTER VAGOTOMY: A COMPARISON OF DRAINAGE PROCEDURES.迷走神经切断术后脂肪泻与腹泻：引流术的比较
Gut. 1964 Apr;5(2):188-91. doi: 10.1136/gut.5.2.188.
3
BOWEL HABIT AFTER VAGOTOMY AND GASTROJEJUNOSTOMY.迷走神经切断术和胃空肠吻合术后的排便习惯。
Br Med J. 1964 Feb 22;1(5381):460-5. doi: 10.1136/bmj.1.5381.460.
4
Hormonal content and effect on gallbladder of commercial preparations of cholecystokinin-pancreozymin.胆囊收缩素-促胰酶素商业制剂的激素含量及其对胆囊的作用
Horm Metab Res. 1981 Aug;13(8):446-50. doi: 10.1055/s-2007-1019297.
5
Effect of vagotomy on exocrine pancreatic and biliary secretion in man.迷走神经切断术对人体胰腺外分泌和胆汁分泌的影响。
Am J Surg. 1981 Jan;141(1):40-7. doi: 10.1016/0002-9610(81)90009-x.
6
Effect of ranitidine, a new H2-antagonist, on gastric and pancreatic secretion in duodenal ulcer patients.新型H2拮抗剂雷尼替丁对十二指肠溃疡患者胃和胰腺分泌的影响。
Dig Dis Sci. 1980 Oct;25(10):737-43. doi: 10.1007/BF01345291.
7
Faecal fat excretion and stool colour after vagotomy and pyloroplasty.迷走神经切断术和幽门成形术后的粪便脂肪排泄及大便颜色
Br Med J. 1966 May 14;1(5497):1194-7. doi: 10.1136/bmj.1.5497.1194.
8
Effect of vagotomy on pancreatic secretion stimulated by endogenous and exogenous secretin.迷走神经切断术对内源性和外源性促胰液素刺激胰腺分泌的影响。
Gastroenterology. 1971 Mar;60(3):425-31.
9
Gastric incontinence and post-vagotomy diarrhoea.胃失禁与迷走神经切断术后腹泻
Br J Surg. 1970 Oct;57(10):741-7. doi: 10.1002/bjs.1800571012.
10
Highly selective vagotomy without a drainage procedure in the treatment of duodenal ulcer.高选择性迷走神经切断术联合非引流手术治疗十二指肠溃疡
Br J Surg. 1970 Apr;57(4):289-96. doi: 10.1002/bjs.1800570414.

高选择性迷走神经切断术对胰腺外分泌功能及胆囊收缩素和胃泌素释放的影响。

Effect of highly selective vagotomy on pancreatic exocrine function and on cholecystokinin and gastrin release.

作者信息

Ramus N I, Williamson R C, Oliver J M, Johnston D

出版信息

Gut. 1982 Jul;23(7):553-7. doi: 10.1136/gut.23.7.553.

DOI:10.1136/gut.23.7.553
PMID:6177587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1419780/
Abstract

The effect of highly selective vagotomy on pancreatic exocrine function and the release of gastrin and cholecystokinin was studied in 10 patients with endoscopically-proven duodenal ulceration. Cholecystokinin and gastrin concentrations in serum both increased significantly after highly selective vagotomy. Amylase concentration in the duodenal aspirate increased significantly after vagotomy, but trypsin concentration remained unchanged. The expected reductions in gastric acid secretion were noted. Thus highly selective vagotomy reduces acid secretion effectively in patients with duodenal ulcer without impairing the exocrine function of the pancreas.

摘要

在10例经内镜证实为十二指肠溃疡的患者中，研究了高选择性迷走神经切断术对胰腺外分泌功能以及胃泌素和胆囊收缩素释放的影响。高选择性迷走神经切断术后，血清中胆囊收缩素和胃泌素浓度均显著升高。迷走神经切断术后十二指肠抽吸物中的淀粉酶浓度显著升高，但胰蛋白酶浓度保持不变。观察到胃酸分泌出现预期的减少。因此，高选择性迷走神经切断术能有效降低十二指肠溃疡患者的胃酸分泌，且不损害胰腺的外分泌功能。