高选择性迷走神经切断术对胰腺外分泌功能及胆囊收缩素和胃泌素释放的影响。
Effect of highly selective vagotomy on pancreatic exocrine function and on cholecystokinin and gastrin release.
作者信息
Ramus N I, Williamson R C, Oliver J M, Johnston D
出版信息
Gut. 1982 Jul;23(7):553-7. doi: 10.1136/gut.23.7.553.
Abstract
The effect of highly selective vagotomy on pancreatic exocrine function and the release of gastrin and cholecystokinin was studied in 10 patients with endoscopically-proven duodenal ulceration. Cholecystokinin and gastrin concentrations in serum both increased significantly after highly selective vagotomy. Amylase concentration in the duodenal aspirate increased significantly after vagotomy, but trypsin concentration remained unchanged. The expected reductions in gastric acid secretion were noted. Thus highly selective vagotomy reduces acid secretion effectively in patients with duodenal ulcer without impairing the exocrine function of the pancreas.
摘要
在10例经内镜证实为十二指肠溃疡的患者中，研究了高选择性迷走神经切断术对胰腺外分泌功能以及胃泌素和胆囊收缩素释放的影响。高选择性迷走神经切断术后，血清中胆囊收缩素和胃泌素浓度均显著升高。迷走神经切断术后十二指肠抽吸物中的淀粉酶浓度显著升高，但胰蛋白酶浓度保持不变。观察到胃酸分泌出现预期的减少。因此，高选择性迷走神经切断术能有效降低十二指肠溃疡患者的胃酸分泌，且不损害胰腺的外分泌功能。
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Effect of highly selective vagotomy on pancreatic exocrine function and on cholecystokinin and gastrin release.高选择性迷走神经切断术对胰腺外分泌功能及胆囊收缩素和胃泌素释放的影响。
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