Wantzin G L, Hou-Jensen K, Nielsen M, Petri J, Thomsen K
Acta Derm Venereol. 1982;62(2):119-24.
25 cases of cutaneous lymphocytoma were reviewed, of which 13 were benign lymphocytoma of the skin and 15 lymphocytic infiltration of the skin (Jessner). The clinical diagnosis benign lymphocytoma of the skin was in agreement with the histology, except in 2 patients where lymphocytic infiltration of the skin (Jessner) was the most likely clinical diagnosis. Of the 15 patients treated, 8 went into complete remission and 5 into partial remission. Eight patients suffered a relapse after partial and complete remission. The duration of the follow-up period varied between 2 months and 22 years. The histological diagnosis lymphocytic infiltration of the skin (Jessner) tallied in 9 patients with the clinical diagnosis, whereas in 6 patients the clinical diagnosis was benign lymphocytoma or pseudolymphoma. None of the patients developed systemic malignancy within the lymphoreticular system. A suspicious-looking skin lesion should always require further examination in order to exclude cutaneous manifestations of a systemic malignant lymphoreticular disease. The present histologic review demonstrates some uncertainty in diagnosing cutaneous lymhocytomas.l
对25例皮肤淋巴细胞瘤进行了回顾性研究，其中13例为皮肤良性淋巴细胞瘤，15例为皮肤淋巴细胞浸润（杰斯纳氏病）。皮肤良性淋巴细胞瘤的临床诊断与组织学诊断相符，但有2例患者最可能的临床诊断为皮肤淋巴细胞浸润（杰斯纳氏病）。在接受治疗的15例患者中，8例完全缓解，5例部分缓解。8例患者在部分缓解和完全缓解后复发。随访期从2个月到22年不等。皮肤淋巴细胞浸润（杰斯纳氏病）的组织学诊断在9例患者中与临床诊断相符，而在6例患者中临床诊断为良性淋巴细胞瘤或假性淋巴瘤。所有患者均未在淋巴网状系统内发生系统性恶性肿瘤。外观可疑的皮肤病变应始终进行进一步检查，以排除系统性恶性淋巴网状疾病的皮肤表现。目前的组织学回顾表明，在诊断皮肤淋巴细胞瘤方面存在一些不确定性。
