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短波紫外线（UVB）对豚鼠迟发型超敏反应的影响。

Effects of short-wave ultraviolet light (UVB) on delayed hypersensitivity in the guinea pig.

作者信息

Austad J, Mørk N J

出版信息

Acta Derm Venereol. 1982;62(2):133-6.

PMID:6179336
Abstract

Guinea pigs, previously sensitized to dinitrochlorobenzene (DNCB), were exposed to varying doses of UVB radiation on the right flank for a period of 12 days. The response to an elicitation dose of DNCB was diminished in the irradiated skin immediately after UV treatment. This effect was dose-dependent. No reduction in the response could be demonstrated in unexposed skin. One week after UVB treatment the response to DNCB was increased, and after 2 weeks there was a normal eczematous reaction after application of DNCB.

摘要

先前对二硝基氯苯（DNCB）致敏的豚鼠，右侧胁腹接受不同剂量的UVB辐射，持续12天。UV治疗后，立即照射部位皮肤对激发剂量的DNCB的反应减弱。这种效应呈剂量依赖性。未照射的皮肤未显示反应降低。UVB治疗1周后，对DNCB的反应增强，2周后，应用DNCB后出现正常的湿疹反应。

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引用本文的文献

1
[Ultraviolet therapy in patients with chronic hand eczema].[慢性手部湿疹患者的紫外线治疗]
Hautarzt. 2008 Sep;59(9):696-702. doi: 10.1007/s00105-008-1558-3.
2
Effect of a single UVB or PUVA exposure on immediate and delayed skin hypersensitivity reactions in humans. Correlation to erythemal response and Langerhans cell depletion.单次紫外线B（UVB）或补骨脂素加长波紫外线（PUVA）照射对人体即刻和延迟皮肤超敏反应的影响。与红斑反应及朗格汉斯细胞耗竭的相关性。
Arch Dermatol Res. 1983;275(6):374-8. doi: 10.1007/BF00417336.
3
Suppression of delayed-type hypersensitivity to histocompatibility antigens by ultraviolet radiation.
紫外线辐射对组织相容性抗原迟发型超敏反应的抑制作用。
Immunology. 1987 Oct;62(2):299-305.