Friedman W H, Katsantonis G P, Slavin R G, Kannel P, Linford P
Otolaryngol Head Neck Surg. 1982 Mar-Apr;90(2):171-7. doi: 10.1177/019459988209000205.
Fifty patients who underwent intranasal sphenoethmoidectomy at the St Louis University Medical Center between July 1977 and April 1980 have been evaluated with respect to preoperative extent of disease and medication requirement as well as postoperative course and reduction in medication requirements, if any. These patients were followed jointly by the Departments of Allergy and Otolaryngology. Most of these patients were not allergic, and over half had intrinsic asthma. Fifteen of the 50 patients, all asthmatic, gave a history of aspirin sensitivity. Many had had previous nasal surgical treatment for polyps. Patients on large corticosteroid dosages had long-lasting reductions or elimination of their corticosteroid requirements in most cases. Similarly, most patients had long-lasting nasal airway improvement and reduction or elimination of recurring sinusitis. Antibiotics and antihistamine-decongestant preparations were sharply diminished in these patients. Although aspirin sensitivity was associated with some of the more severe asthmatic patients, it appeared not to be a factor in the responses to surgical treatment.
1977年7月至1980年4月期间，在圣路易斯大学医学中心接受鼻内蝶筛窦切除术的50例患者，就术前疾病范围、药物需求以及术后病程和药物需求减少情况（若有）进行了评估。这些患者由过敏科和耳鼻喉科联合随访。这些患者大多无过敏反应，半数以上患有内源性哮喘。50例患者中有15例（均为哮喘患者）有阿司匹林敏感性病史。许多患者既往曾因息肉接受过鼻腔手术治疗。在大多数情况下，接受大剂量皮质类固醇治疗的患者其皮质类固醇需求长期减少或消除。同样，大多数患者的鼻气道长期改善，复发性鼻窦炎减轻或消除。这些患者使用的抗生素和抗组胺减充血剂制剂大幅减少。虽然阿司匹林敏感性与一些病情较重的哮喘患者有关，但它似乎不是影响手术治疗反应的因素。
