Shutov A A, Prostakova T I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(6):49-53.
Using the method of concurrent radioisotope in-vitro analysis the authors examined the serum levels of thyroid hormones in 70 patients with temporal epilepsy. As a result of the examination two groups of the cases could be differentiated. In 53 patients the hormonal activity of the thyroid appeared to be lowered, while in 17 patients it was increased. A certain relationship between the clinical manifestations and course of the epilepsy on the one hand, and thyroid function on the other was revealed. More unfavourable variants of the epilepsy were found to be associated with subclinical hypothyrosis. The following phenomena are assumed to be criteria of the unfavourable course of epilepsy: a greater frequency of general convulsive paroxysms and epileptic states, early development and steady progress of the intellectual and emotional impairments; more marked and diffuse disorganization of the brain bioelectrical activity, and loss of the elastic properties by cerebral vessels.
作者采用放射性同位素体外同步分析方法，检测了70例颞叶癫痫患者的血清甲状腺激素水平。检查结果可将病例分为两组。53例患者甲状腺激素活性降低，17例患者甲状腺激素活性升高。揭示了癫痫的临床表现和病程与甲状腺功能之间的某种关系。发现癫痫更不利的变体与亚临床甲状腺功能减退有关。以下现象被认为是癫痫病程不利的标准：全身性惊厥发作和癫痫状态的频率更高，智力和情感障碍的早期发展和稳定进展；脑生物电活动更明显和弥漫性紊乱，以及脑血管弹性丧失。
