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[颞叶癫痫患者的碘代谢状况]

[State of iodine metabolism in patients with temporal lobe epilepsy].

作者信息

Shutov A A, Pleshkova N M, Prostakova T I

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(3):384-8.

PMID:857529
Abstract

Using a radioisotope concurrent analysis the authors studied the concentration of general thyroxine (T4), the coefficient of effective thyroxine, the equivalent content of free thyroxine in the blood serum and the fixating capabilities of plasma protein in relation to T3 in patients with temporal epilepsy. The study depicted complex changes of the hormonal activity of the thyroid gland. Considering the amount of the index of free thyroxine and coefficient of effective thyroxine, the state of the thyroid gland in cases of dissociated indices was qualified as hypo-, hyper- and euthyroid (respectively in 3, 8 and 10 patients). The authors discuss the possible pathogenetical significance of changes in the hormonal activity of the thyroid gland.

摘要

作者采用放射性同位素同步分析方法,研究了颞叶癫痫患者血清中总甲状腺素(T4)的浓度、有效甲状腺素系数、游离甲状腺素的等效含量以及血浆蛋白对T3的结合能力。该研究描述了甲状腺激素活性的复杂变化。根据游离甲状腺素指数和有效甲状腺素系数的数值,将指标分离的病例中的甲状腺状态分为甲状腺功能减退、甲状腺功能亢进和甲状腺功能正常(分别为3例、8例和10例患者)。作者讨论了甲状腺激素活性变化可能的发病机制意义。

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