Smullens S N, Scotti D J, Osterholm J L, Weiss A J
Cancer. 1982 Nov 1;50(9):1870-5. doi: 10.1002/1097-0142(19821101)50:9<1870::aid-cncr2820500936>3.0.co;2-s.
The first reported cases of preoperatively embolized hemangiopericytomas are presented. Both lesions presented in the retroperitoneum where most lesions are now considered to be malignant. In the past, the highly vascular nature of these tumors has made resection in these areas difficult. Since the angiographic picture of hemangiopericytomas is now thought to be specific, it became feasible to add preoperative embolization to the overall management of these cases. In the first case, the diagnosis had been established 15 years previously. When first seen at Thomas Jefferson University Hospital, extensive bone destruction of the sacrum and lumbar vertebrae were present. Preoperative Gelfoam embolization aided in the palliative debulking of the tumor at operation. With this experience, preoperative embolization became part of the management in the second case and aided in the complete surgical removal of the tumor. Radiation therapy in the dosage of 5000 rad was given postoperatively in this case and should also be part of the treatment plan for these lesions.
本文报道了首例术前栓塞的血管外皮细胞瘤病例。两个病变均位于腹膜后,目前大多数该部位的病变被认为是恶性的。过去,这些肿瘤的高血管性质使得在这些区域进行切除手术很困难。由于现在认为血管外皮细胞瘤的血管造影表现具有特异性,因此在这些病例的整体治疗中增加术前栓塞变得可行。在第一例中,诊断在15年前就已确立。当患者首次在托马斯·杰斐逊大学医院就诊时,骶骨和腰椎出现广泛骨质破坏。术前明胶海绵栓塞有助于术中肿瘤的姑息性减瘤。基于这一经验,术前栓塞成为第二例病例治疗的一部分,并有助于肿瘤的完整手术切除。该病例术后给予了5000拉德的放射治疗,放射治疗也应成为这些病变治疗计划的一部分。