色甘酸钠和环磷酸腺苷活性药物对大鼠肥大细胞细胞毒性组胺释放的影响。
Effect of disodium cromoglycate and cyclic AMP-active drugs on cytotoxic histamine release from rat mast cells.
作者信息
Pearce F L, Clements J
出版信息
Biochem Pharmacol. 1982 Jul 1;31(13):2247-50. doi: 10.1016/0006-2952(82)90109-5.
PMID:6181790
Abstract
Disodium cromoglycate and compounds which elevated levels of cyclic AMP in the mast cell variously inhibited cytotoxic histamine release induced by the surface active agents melittin, Tween 20 and Triton X-100. These results are inconsistent with the postulated effects of the drugs on receptor mediated calcium channels and alternative explanations of their action are considered.
摘要
色甘酸钠以及能提高肥大细胞中环磷酸腺苷水平的化合物，不同程度地抑制了由表面活性剂蜂毒肽、吐温20和曲拉通X-100诱导的细胞毒性组胺释放。这些结果与药物对受体介导的钙通道的假定作用不一致，并对其作用的其他解释进行了探讨。
Zotero 插件