Gomes J C, Pearce F L
Department of Chemistry, University College London, UK.
Agents Actions. 1988 Jul;24(3-4):266-71. doi: 10.1007/BF02028282.
The effects of a number of non-steroidal anti-inflammatory drugs (NSAID) on histamine secretion from tissue mast cells of the rat and the guinea pig have been examined. According to the experimental conditions and cell type, the drugs potentiated, inhibited or had no effect on histamine release. The possible mechanisms of these effects are discussed.
已对多种非甾体抗炎药(NSAID)对大鼠和豚鼠组织肥大细胞组胺分泌的影响进行了研究。根据实验条件和细胞类型,这些药物对组胺释放有增强、抑制或无作用。讨论了这些作用的可能机制。