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非甾体抗炎药(NSAID)对大鼠和豚鼠肥大细胞组胺释放影响的比较研究。

Comparative studies on the effect of non-steroidal anti-inflammatory drugs (NSAID) on histamine release from mast cells of the rat and guinea pig.

作者信息

Gomes J C, Pearce F L

机构信息

Department of Chemistry, University College London, UK.

出版信息

Agents Actions. 1988 Jul;24(3-4):266-71. doi: 10.1007/BF02028282.

Abstract

The effects of a number of non-steroidal anti-inflammatory drugs (NSAID) on histamine secretion from tissue mast cells of the rat and the guinea pig have been examined. According to the experimental conditions and cell type, the drugs potentiated, inhibited or had no effect on histamine release. The possible mechanisms of these effects are discussed.

摘要

已对多种非甾体抗炎药(NSAID)对大鼠和豚鼠组织肥大细胞组胺分泌的影响进行了研究。根据实验条件和细胞类型,这些药物对组胺释放有增强、抑制或无作用。讨论了这些作用的可能机制。

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