Jensen O A, Norn M S
Acta Ophthalmol (Copenh). 1982 Feb;60(1):79-92. doi: 10.1111/j.1755-3768.1982.tb05784.x.
Sixteen specimens from 14 patients with typical conjunctival spheroid bodies were obtained by biopsy. Six biopsies were examined histochemically and 10 ultrastructurally. For comparison tissue from pingueculae was processed simultaneously in 4 cases for light microscopy and in one for electron microscopy. The spheroid bodies were found to be strongly autofluorescent and of a proteinaceous nature, corresponding to the elastotic degeneration in pingueculae. Ultrastructurally they were of various electron density, but when distinguishable the fine structure was granular with transition from surrounding collagen fibres. Based on reports from the literature and on our own investigations, it is concluded that condensations seen as spheroid bodies in both conjunctival and corneal tissue under solar/climatic influence are similar and have their origin in degenerated collagen.
从14例患有典型结膜球状体的患者身上获取了16个活检标本。对6个活检标本进行了组织化学检查，10个进行了超微结构检查。为作比较，同时对4例睑裂斑组织进行了光镜处理，1例进行了电镜处理。发现球状体具有强烈的自发荧光且具有蛋白质性质，与睑裂斑中的弹性变性相对应。在超微结构上，它们具有不同的电子密度，但当可区分时，其精细结构呈颗粒状，与周围胶原纤维过渡相连。根据文献报道和我们自己的研究，得出结论：在阳光/气候影响下，在结膜和角膜组织中视为球状体的凝聚物是相似的，并且起源于变性的胶原。
