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发育中小鼠大脑中α-甲胎蛋白在神经元内定位的区域差异

Regional differences in intraneuronal localization of alpha-fetoprotein in developing mouse brain.

作者信息

Toran-Allerand C D

出版信息

Brain Res. 1982 Oct;281(2):213-7. doi: 10.1016/0165-3806(82)90161-4.

DOI:10.1016/0165-3806(82)90161-4
PMID:6182956
Abstract

Estrogen receptor-containing regions of limbic, hypothalamic and amygdaloid areas of the developing mouse brain exhibited little or no intraneuronal immunofluorescence reactivity for AFP in comparison with the bright fluorescence of adjacent regions. These regional differences in the topographic distribution of intraneuronal AFP may represent intrinsic differences in the uptake, turnover or immunoreactivity of the internalized protein, perhaps related to estrogen metabolism by such neurons.

摘要

与相邻区域的明亮荧光相比,发育中小鼠大脑边缘系统、下丘脑和杏仁核区域含雌激素受体的部位对甲胎蛋白几乎没有或没有神经元内免疫荧光反应。神经元内甲胎蛋白在这些区域分布的差异可能代表内化蛋白在摄取、周转或免疫反应性方面的内在差异,这可能与这些神经元的雌激素代谢有关。

相似文献

1
Regional differences in intraneuronal localization of alpha-fetoprotein in developing mouse brain.发育中小鼠大脑中α-甲胎蛋白在神经元内定位的区域差异
Brain Res. 1982 Oct;281(2):213-7. doi: 10.1016/0165-3806(82)90161-4.
2
Neuronal uptake of alpha-fetoprotein (AFP) synthesized and secreted by hepatocytes in liver/brain co-cultures.肝/脑共培养体系中,神经元对肝细胞合成与分泌的甲胎蛋白(AFP)的摄取。
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Alpha-fetoprotein in the brain of developing rats and pigs. An immunofluorescent study of cell-and-tissue differentiation.发育中大鼠和猪大脑中的甲胎蛋白。细胞与组织分化的免疫荧光研究。
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[Intracellular localization of alpha-fetoprotein and serum albumin in the central nervous system of the rat during fetal and postnatal development].[大鼠胎儿期及出生后发育过程中中枢神经系统内甲胎蛋白和血清白蛋白的细胞内定位]
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Immunocytochemical localization of alpha-fetoprotein in the developing rat brain.甲胎蛋白在发育中大鼠脑内的免疫细胞化学定位
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Alpha-fetoprotein in the brain of embryonic pigs.胚胎猪大脑中的甲胎蛋白。
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[The localization of alpha-fetoprotein in the mouse fetus by immunofluorescence and immunodiffusion tests].[通过免疫荧光和免疫扩散试验对小鼠胎儿中甲胎蛋白的定位]
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Alpha-fetoprotein (AFP) modulates the effect of serum albumin on brain development by restraining the neurotrophic effect of oleic acid.甲胎蛋白(AFP)通过抑制油酸的神经营养作用来调节血清白蛋白对大脑发育的影响。
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Intracellular uptake of alpha-fetoprotein: a marker of neural differentiation.甲胎蛋白的细胞内摄取:神经分化的一个标志物。
Ann N Y Acad Sci. 1983;417:321-9. doi: 10.1111/j.1749-6632.1983.tb32875.x.

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Endocrinology. 2008 Jun;149(6):3054-61. doi: 10.1210/en.2007-1133. Epub 2008 Feb 28.
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The distribution of plasma proteins during early embryonic development in the sheep.
绵羊早期胚胎发育过程中血浆蛋白的分布
Anat Embryol (Berl). 1983;168(2):227-40. doi: 10.1007/BF00315818.
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Immunocytochemical localization of albumin in ovarian follicles of fertile rats.白蛋白在受孕大鼠卵巢卵泡中的免疫细胞化学定位。
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The special case of hormonal imprinting, the neonatal influence of sex.激素印记的特殊情况,即性别对新生儿的影响。
Experientia. 1986 Jul 15;42(7):759-69. doi: 10.1007/BF01941522.