Keprtová J, Minárová E, Michl J, Spurná V
Folia Biol (Praha). 1982;28(4):225-32.
The growth-promoting alpha-globulin necessary for long-term cultivation of mammalian cells in serum-free medium is a complex of several proteins which also stimulates the incorporation of exogenous DNA into recipient L cells. Biological activity responsible for the stimulation of DNA incorporation into L cells can be concentrated because one of two major protein components, compared to the whole GPAG complex, increases incorporation into cell nuclei by 100%.
在无血清培养基中对哺乳动物细胞进行长期培养所必需的促生长α球蛋白是几种蛋白质的复合物，它还能刺激外源DNA掺入受体L细胞。负责刺激DNA掺入L细胞的生物活性可以被浓缩，因为与整个GPAG复合物相比，两种主要蛋白质成分之一能使进入细胞核的掺入量增加100%。
