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外源DNA的掺入及其在宿主细胞染色体中的定位。

Incorporation of exogenous DNA and its localization in the chromosomes of the host cell.

作者信息

Mińarrová E, Keprtová J, Nebola M, Spurná V

出版信息

Neoplasma. 1975;22(5):491-4.

PMID:1196432
Abstract

Incorporation of isologous 3H-DNA of exogenous origin into chromosomes of the L cells was investigated by means of autoradiographical technique. It was shown that during short time intervals of incubation of 3H-DNA with the host cells (1--3 hr), nearly double quantity of the mitoses was labelled, when compared with 3H-TdR used as a control. During longer time intervals, no difference between number of the mitoses labelled with 3H-TdR and exogenous isologous 3H-DNA was observed.

摘要

利用放射自显影技术研究了外源同源3H-DNA掺入L细胞染色体的情况。结果表明,在3H-DNA与宿主细胞短时间孵育(1-3小时)期间,与用作对照的3H-TdR相比,标记的有丝分裂数量几乎增加了一倍。在较长时间间隔内,未观察到用3H-TdR和外源同源3H-DNA标记的有丝分裂数量之间的差异。

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Incorporation of exogenous DNA and its localization in the chromosomes of the host cell.外源DNA的掺入及其在宿主细胞染色体中的定位。
Neoplasma. 1975;22(5):491-4.
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